Metabolic syndrome in antipsychotic naïve patients with schizophrenia: pooled analysis of data from three Indian studies. Issue 5 (20th January 2014)

• Record Type: Journal Article
• Authors: Grover, Sandeep; Nebhinani, Naresh; Padmavati, Ramachandran; Chadda, Rakesh K; Tirupati, Srinivasan; Pallava, Abhishek
• Is Part Of: Early intervention in psychiatry. Volume 9:Issue 5(2015:Oct.)
• Page Start: 357
• Page End: 362
• Publication Date: 2014-01-20
• Subjects: drug naïve -- metabolic syndrome -- schizophrenia; Mental health -- Periodicals; Psychiatry -- Periodicals; Psychiatry -- Research -- Periodicals; Mental illness -- Prevention -- Research -- Periodicals; Mental illness -- Treatment -- Research -- Periodicals; 616.89
• DOI: 10.1111/eip.12117
• Languages: English
• ISSNs: 1751-7885

Abstract

Abstract: Aim: This study aimed to assess the prevalence of metabolic syndrome (MS) and subthreshold MS in antipsychotic naïve patients with schizophrenia by pooling the data from three different centres in India. Methods: One hundred thirty‐seven antipsychotic naïve patients with schizophrenia were evaluated for MS using common criteria for clinical diagnosis. Results: Twenty‐six patients (19%) met consensus criteria. Additionally, 56 patients (40.9%) fulfilled one criterion and 32 patients (23.3%) fulfilled two criteria of MS out of five criteria. Conclusion: One‐fifth of antipsychotic naïve patients with schizophrenia had MS and another two‐third had at least one metabolic abnormality. Awareness of such a high risk is vitally important for rational selection of antipsychotic medications as well as effective implementation of preventive measures.