Catheter‐related thrombosis in cancer patients. (15th July 2013)

• Record Type: Journal Article
• Authors: Murray, Jim; Precious, Elizabeth; Alikhan, Raza
• Is Part Of: British journal of haematology. Volume 162:Number 6(2013:Sep.)
• Page Start: 748
• Page End: 757
• Publication Date: 2013-07-15
• Subjects: cancer -- venous thrombosis -- central venous catheter -- anticoagulation; Hematology -- Periodicals; Blood -- Diseases -- Periodicals; 616.15
• DOI: 10.1111/bjh.12474
• Languages: English
• ISSNs: 0007-1048

Abstract

Summary: Central venous catheters are commonly used in haematology departments for the administration of chemotherapy, blood products and parenteral nutrition in patients with haematological malignancy. Thrombosis is a recognized complication of such devices especially in oncology patients. Catheter‐related thrombi (CRT) may lead to pulmonary embolism and infection, as well as catheter failure and potential delays in treatment. The vast majority of CRT are asymptomatic, thus a high index of suspicion is required in making the diagnosis. Doppler ultrasound or venography may be employed to identify CRT. Once confirmed, the initiation of treatment is a balance between the risks of anticoagulation against potential complications of CRT. A number of risk factors for CRT are discussed along with an overview of catheter types, their appropriate choice and intravascular positioning.