Cardiac Amyloidosis Presenting With Cardiogenic Shock. (July 2016)

• Record Type: Journal Article
• Authors: Afzal, Ashwad; Brener, Sorin J.; Narula, Navneet; Worku, Berhane; Gulkarov, Iosif
• Is Part Of: American journal of therapeutics. Volume 23:Number 4(2016)
• Publication Date: 2016-07
• Subjects: amyloidosis -- cardiac amyloidosis; Chemotherapy -- Periodicals; Pharmacology -- Periodicals; 615.58
• DOI: 10.1097/MJT.0000000000000293
• Languages: English
• ISSNs: 1075-2765

Abstract

Abstract : Cardiac amyloidosis is an infiltrative disorder of the myocardium. It is the result of one of 4 types of amyloidosis: primary systemic (immunoglobulin light chain), secondary, familial (hereditary), or senile. Cardiac amyloidosis ultimately causes congestive heart failure due to irreversible restrictive cardiomyopathy. Because of the rapid progression of the disease, early recognition and determination of underlying etiology are important for tailored therapy. Current interventions range from conservative heart failure management to autologous stem cell and heart transplantation. We present a case of cardiac amyloidosis accompanying undiagnosed multiple myeloma to illustrate the rapid progression of the disease and the complexities of diagnosing and treating this disorder.