RISK OF RHEGMATOGENOUS RETINAL DETACHMENT WITH CENTRAL SEROUS CHORIORETINOPATHY. Issue 8 (August 2016)

• Record Type: Journal Article
• Authors: Chang, Yuh-Shin; Chang, Chun; Weng, Shih-Feng; Wang, Jhi-Joung; Jan, Ren-Long
• Is Part Of: Retina. Volume 36:Issue 8(2016:Aug.)
• Publication Date: 2016-08
• Subjects: central serous chorioretinopathy -- National Health Insurance Research Database -- population-based study -- rhegmatogenous retinal detachment; Retina -- Diseases -- Periodicals; Retinal Diseases; Vitreous Body; 617.735
• DOI: 10.1097/IAE.0000000000000946
• Languages: English
• ISSNs: 0275-004X

Abstract

Abstract : Purpose: To investigate the risk of rhegmatogenous retinal detachment (RRD) after central serous chorioretinopathy (CSCR). Methods: The study included 2, 830 patients with CSCR and 16, 980 control patients matched using a propensity score for age, sex, and comorbidities including status after cataract operation, blunt trauma, myopia, diabetes mellitus, hypertension, and hyperlipidemia from January 2001 through December 2010 from the Taiwan Longitudinal Health Insurance Database 2000. Information of each patient was collected until December 2011. Cox proportional hazard regression analysis was used to obtain the adjusted hazard ratio for RRD. The RRD-free survival rate was calculated using Kaplan–Meier analysis. Results: Thirty-five patients with CSCR (1.24%) and 27 controls (0.16%) had RRD ( P < 0.0001) during follow-up, resulting in a significantly higher risk of RRD in the patients with CSCR (incidence rate ratio = 7.83, 95% confidence interval = 4.74–12.93). After adjustment for potential confounders, the adjusted hazard ratio for developing RRD was increased 7.85 times in the cohort of total sample (adjusted hazard ratio = 7.85, 95% confidence interval = 4.75–12.97). Conclusion: It was found that CSCR increased the risk of RRD even after adjustment for age, sex, and comorbidities including status after cataract operation, blunt trauma, myopia, diabetes mellitus, hypertension, and hyperlipidemia. Abstract : This population-based cohort study investigates the association between central serous chorioretinopathy and rhegmatogenous retinal detachment. Patients with central serous chorioretinopathy showed a high incidence rate of rhegmatogenous retinal detachment and maintained significant risk of rhegmatogenous retinal detachment after adjustment for other confounders. The authors recommend thorough peripheral retinal examinations and education regarding rhegmatogenous retinal detachment for patients with central serous chorioretinopathy.