Subacute Stroke Mimicking Cerebral Metastasis in 68Ga-PSMA-HBED-CC PET/CT. (October 2016)

• Record Type: Journal Article
• Authors: Noto, Benjamin; Vrachimis, Alexis; Schäfers, Michael; Stegger, Lars; Rahbar, Kambiz
• Is Part Of: Clinical nuclear medicine. Volume 41:Number 10(2016)
• Publication Date: 2016-10
• Subjects: PSMA -- PET/CT -- cerebral metastasis -- ischemic stroke -- MRI -- pitfall -- GCPII; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000001291
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: A 65-year-old man with disseminated bone metastases of prostate cancer was referred for 68 Ga-PSMA-HBED-CC-PET/CT (short PSMA-PET/CT) to exclude visceral metastases before treatment of bone metastases with 223 Ra-dichloride. Apart from disseminated bone metastases, PSMA-PET/CT revealed a focal cerebral tracer uptake in the right frontal lobe highly suspicious for cerebral spread. According to patient history, a cerebral infarction occurred 14 days before PSMA imaging in corresponding localization confirmed by MRI scanning. This case demonstrates the possibility of false-positive finding of cerebral metastases in PSMA-PET early after stroke.