Endolymphatic Sac Tumor Showing Increased Activity on 68Ga DOTATATE PET/CT. (October 2016)

• Record Type: Journal Article
• Authors: Papadakis, Georgios Z.; Millo, Corina; Sadowski, Samira M.; Bagci, Ulas; Patronas, Nicholas J.
• Is Part Of: Clinical nuclear medicine. Volume 41:Number 10(2016)
• Publication Date: 2016-10
• Subjects: endolymphatic sac tumors -- von Hippel-Lindau disease -- 68Ga-DOTATATE PET/CT -- somatostatin receptors-imaging; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000001315
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: Endolymphatic sac tumors (ELSTs) are rare tumors arising from the epithelium of the endolymphatic sac and duct that can be either sporadic or associated with von Hippel-Lindau (VHL) disease. We report a case of a VHL patient with histologically proven residual ELST who underwent 68 Ga DOTATATE PET/CT showing increased activity (SUVmax, 6.29) by the ELST. The presented case of a VHL-associated ELST with increased 68 Ga DOTATATE uptake indicates cell-surface expression of somatostatin receptors by this tumor, suggesting the potential application of somatostatin receptor imaging using 68 Ga DOTA-conjugated peptides in the workup and management of these patients.