18F-DOPA Uptake of Developmental Venous Anomalies in Children With Brain Tumors. (July 2016)

• Record Type: Journal Article
• Authors: Morana, Giovanni; Piccardo, Arnoldo; Garrè, Maria Luisa; Cabria, Manlio; Rossi, Andrea
• Is Part Of: Clinical nuclear medicine. Volume 41:Number 7(2016)
• Publication Date: 2016-07
• Subjects: DOPA PET -- pediatric -- brain MRI -- developmental venous anomaly -- venous angioma; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000001189
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: We report the finding of increased 18 F-3, 4-dihydroxyphenylalanine uptake of the brain parenchyma adjacent to developmental venous anomalies, incidentally discovered in 3 pediatric patients with diffusely infiltrating gliomas. One patient presented 3 developmental venous anomalies located distant from the tumor, whereas in the remaining 2 patients, the vascular anomalies were inside the tumoral area mimicking a focal area of increased tumor metabolism. In the setting of brain tumor imaging, focal increased 18 F-3, 4-dihydroxyphenylalanine uptake should be carefully interpreted in light of MRI findings, and nuclear medicine physicians should be aware of any incidental minor vascular abnormality for proper interpretation of PET data.