Implementation and Performance of Automated Software for Computing Right-to-Left Ventricular Diameter Ratio From Computed Tomography Pulmonary Angiography Images. Issue 3 (May 2016)

• Record Type: Journal Article
• Authors: Kumamaru, Kanako K.; George, Elizabeth; Aghayev, Ayaz; Saboo, Sachin S.; Khandelwal, Ashish; Rodríguez-López, Sara; Cai, Tianrun; Jiménez-Carretero, Daniel; Estépar, Raúl San José; Ledesma-Carbayo, Maria J.; González, Germán; Rybicki, Frank J.
• Is Part Of: Journal of computer assisted tomography. Volume 40:Issue 3(2016)
• Publication Date: 2016-05
• Subjects: pulmonary embolism -- computer-aided detection -- prognosis -- right ventricular strain -- diameter ratio; Tomography -- Periodicals; Tomography -- Periodicals; Tomography; Periodicals; 616.0757
• DOI: 10.1097/RCT.0000000000000375
• Languages: English
• ISSNs: 0363-8715

Abstract

Abstract : Objective: The aim of this study was to prospectively test the performance and potential for clinical integration of software that automatically calculates the right-to-left ventricular (RV/LV) diameter ratio from computed tomography pulmonary angiography images. Methods: Using 115 computed tomography pulmonary angiography images that were positive for acute pulmonary embolism, we prospectively evaluated RV/LV ratio measurements that were obtained as follows: (1) completely manual measurement (reference standard), (2) completely automated measurement using the software, and (3 and 4) using a customized software interface that allowed 2 independent radiologists to manually adjust the automatically positioned calipers. Results: Automated measurements underestimated ( P < 0.001) the reference standard (1.09 [0.25] vs1.03 [0.35]). With manual correction of the automatically positioned calipers, the mean ratio became closer to the reference standard (1.06 [0.29] by read 1 and 1.07 [0.30] by read 2), and the correlation improved ( r = 0.675 to 0.872 and 0.887). The mean time required for manual adjustment (37 [20] seconds) was significantly less than the time required to perform measurements entirely manually (100 [23] seconds). Conclusions: Automated CT RV/LV diameter ratio software shows promise for integration into the clinical workflow for patients with acute pulmonary embolism.