Maxillary Sinus Grafting With Biphasic Bone Ceramic or Autogenous Bone: Clinical, Histologic, and Histomorphometric Results From a Randomized Controlled Clinical Trial. Issue 5 (October 2016)

• Record Type: Journal Article
• Authors: Danesh-Sani, Seyed A.; Wallace, Stephen S.; Movahed, Ali; El Chaar, Edgard S.; Cho, Sang-Choon; Khouly, Ismael; Testori, Tiziano
• Is Part Of: Implant dentistry. Volume 25:Issue 5(2016:Oct.)
• Publication Date: 2016-10
• Subjects: biphasic calcium phosphate -- bone substitute -- autogenous bone sinus augmentation -- sinus floor elevation; Dental implants -- Periodicals; 617.69305
• DOI: 10.1097/ID.0000000000000474
• Languages: English
• ISSNs: 1056-6163

Abstract

Abstract : Purpose: The present, randomized, controlled clinical trial compared the histologic and histomorphometric results from maxillary sinus augmentation with either biphasic calcium phosphate (BCP) (60% hydroxyapatite and 40% β-tricalcium phosphate) or autogenous bone (AB) as bone-grafting materials. Material and Methods: Ten patients received bilateral sinus elevation surgery with intraoral AB chips (control group) on one side and BCP (test group) on the contralateral side. After a healing period of 6 to 8 months, implant sites were created and trephine cores were harvested for histological and histomorphometric analysis of the grafted areas. Results: The histological examination of biopsies showed BCP particles interconnected by bridges of a vital newly formed bone. Histomorphometry demonstrated that the amount of newly formed bone in the control group (36.8%) was significantly greater than that in the BCP (28.2%) group ( P = 0.0032). BCP and AB cores revealed an average of residual graft particles of 32.9% and 4.8%, respectively. The average percentage of soft tissue components was 38.9% in the BCP cores and 58.4% in the AB cores. Conclusions: Based on our findings, the amount of vital bone formation was significantly higher for AB than that for BCP. However, BCP seemed to be a biocompatible and osteoconductive material that can be used with success as a bone substitute in maxillary sinus procedures.