18F-NaF PET/CT Imaging of Brain Metastases. (July 2016)

• Record Type: Journal Article
• Authors: Salgarello, Matteo; Lunardi, Gianluigi; Inno, Alessandro; Pasetto, Stefano; Severi, Fabrizia; Gorgoni, Giancarlo; Gori, Stefania
• Is Part Of: Clinical nuclear medicine. Volume 41:Number 7(2016)
• Publication Date: 2016-07
• Subjects: 18F-NaF -- PET -- brain metastasis; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000001186
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: 18 F-NaF is a radiopharmaceutical widely used in PET imaging to detect bone metastases. Several cases of 18 F-NaF uptake from brain metastases have been described, but a specific protocol for the evaluation of brain metastases with 18 F-NaF has not been developed yet. Here we report images of 18 F-NaF PET/CT, standard CT, and MRI of a brain metastasis in a patient with non–small lung cancer. Through a dynamic acquisition procedure, we have identified the first minutes after injection as the preferable time point of imaging acquisition for the study of brain metastases with 18 F-NaF.