Cutaneous Metastasis of a Mucoepidermoid Carcinoma of the Pancreas: First Reported Case. (November 2016)

• Record Type: Journal Article
• Authors: Pandey, Prasamsa; Al-Rohil, Rami N.; Goldstein, Jennifer B.; Tetzlaff, Michael T.; Barnes, Tamara G.; Baldwin, Sarah E.; Fogelman, David; Abraham, Susan C.; Piha-Paul, Sarina A.
• Is Part Of: American journal of dermatopathology. Volume 38:Number 11(2016)
• Publication Date: 2016-11
• Subjects: mucoepidermoid carcinoma -- pancreas -- cutaneous metastasis; Skin -- Diseases -- Periodicals; Histology, Pathological -- Periodicals; 616.50705
• DOI: 10.1097/DAD.0000000000000604
• Languages: English
• ISSNs: 0193-1091

Abstract

Abstract : Background: Mucoepidermoid pancreatic cancer is a rare entity with only 8 cases reported in the literature. On review of the literature, the authors found that cutaneous metastases in pancreatic cancer are rare and have not been associated with the mucoepidermoid subtype. The authors present the first reported case of cutaneous metastasis in a patient with mucoepidermoid carcinoma of the pancreas. Case Presentation: A 50-year old white male with a metastatic invasive poorly differentiated mucoepidermoid carcinoma of the pancreas was found to have a slow growing lesion in the skin over his left upper quadrant while undergoing active therapy. The lesion was biopsied and the pathology was consistent with pancreatic origin sharing similar morphologic features when compared with the primary pancreactectomy specimen. Conclusions: Mucoepidermoid pancreatic cancer is an exceedingly rare subtype of pancreatic cancer, with very little information regarding its diagnosis, treatment, and patterns of metastases. Here, the authors present the first reported case of cutaneous metastases of mucoepidermoid pancreatic cancer.