Evaluation of Lung Radiofrequency Ablation With Dual-Energy Computed Tomography: Analysis of Tumor Composition and Lung Perfusion. Issue 5 (September 2016)

• Record Type: Journal Article
• Authors: Tomita, Koji; Hiraki, Takao; Gobara, Hideo; Fujiwara, Hiroyasu; Iguchi, Toshihiro; Matsui, Yusuke; Kanazawa, Susumu
• Is Part Of: Journal of computer assisted tomography. Volume 40:Issue 5(2016)
• Publication Date: 2016-09
• Subjects: composition analysis -- dual-energy computed tomography -- lung perfusion -- lung radiofrequency ablation; Tomography -- Periodicals; Tomography -- Periodicals; Tomography; Periodicals; 616.0757
• DOI: 10.1097/RCT.0000000000000422
• Languages: English
• ISSNs: 0363-8715

Abstract

Abstract : Objective: The aim of this study was to evaluate radiofrequency ablation (RFA) of lung tumors with dual-energy computed tomography while focusing on tumor composition and lung perfusion. Methods: The 36 tumors in 25 patients were included. Dual-energy computed tomography was performed before RFA and at 2 days and 1, 3, and 6 months thereafter. The effective atomic number ( Z eff ) of the tumors before RFA was compared with the Z eff at each follow-up using the paired t test. Lung perfusion was evaluated by iodine map images. When decreased perfusion was suspected after RFA, lung perfusion scintigraphy was performed. Results: The mean Z eff of the tumors significantly ( P < 0.001) decreased at each follow-up, compared with that before RFA. Lung perfusion in the parenchyma peripheral to the tumors appeared to decrease at 2 days in 9 tumors, which was confirmed by scintigraphy in 7 tumors. Conclusions: Dual-energy computed tomography was useful by providing additional information on tumor composition and lung perfusion.