Pulmonary Hypertension in the Era of Mechanical Circulatory Support. Issue 5 (September 2016)

• Record Type: Journal Article
• Authors: Krishnamurthy, Yamini; Cooper, Lauren B.; Parikh, Kishan S.; Felker, G. Michael; Milano, Carmelo A.; Rogers, Joseph G.; Hernandez, Adrian F.; Patel, Chetan B.
• Is Part Of: ASAIO journal. Volume 62:Issue 5(2016)
• Publication Date: 2016-09
• Subjects: heart failure -- pulmonary hypertension due to left heart disease -- mechanical circulatory support; Artificial organs -- Periodicals; 617
• DOI: 10.1097/MAT.0000000000000408
• Languages: English
• ISSNs: 1058-2916

Abstract

Abstract : Left heart disease (LHD) represents the most common cause of pulmonary hypertension (PH), and is associated with worse prognosis compared with LHD without PH. In addition, PH due to LHD may prevent patients from receiving heart transplantation, because of risk of perioperative right ventricular failure. Current literature lacks comprehensive descriptions and management strategies of PH due to LHD. In this review, we summarize the literature that is available to highlight the definition, pathogenesis, and prognosis of PH due to LHD. Furthermore, we discuss the use of mechanical circulatory support (MCS) in this population. Finally, we provide recommendations regarding the management and reassessment of PH due to LHD in the specific context of MCS.