Anti‐N‐methyl‐D‐aspartate receptor encephalitis: An atypical presentation with ataxia. Issue 1 (11th January 2017)

• Record Type: Journal Article
• Authors: Barquero‐Madrigal, Alejandro
• Is Part Of: Clinical & experimental neuroimmunology. Volume 8:Issue 1(2017)
• Page Start: 67
• Page End: 70
• Publication Date: 2017-01-11
• Subjects: anti‐N‐methyl‐D‐aspartate receptor encephalitis -- ataxia -- autoimmune encephalitis -- movement disorders -- psychosis; 616.80479
• DOI: 10.1111/cen3.12362
• Languages: English
• ISSNs: 1759-1961

Abstract

Abstract: Anti‐N‐methyl‐D‐aspartate receptor encephalitis is a disorder characterized by psychiatric symptoms, cognitive impairment, movement disorders and autonomic dysfunction; originally thought to be a paraneoplastic syndrome. The classical clinical picture comprises five stages, but there are some milder or incomplete forms of the disorder. A 57‐year‐old man, with no previous psychiatric or comorbid illnesses, presented a clinical picture of initial psychosis followed by ataxia and headache. Serum and cerebrospinal fluid determination of anti‐N‐methyl‐D‐aspartate receptor antibodies confirmed the diagnosis of autoimmune encephalitis. Clinicians should be aware of some psychiatric manifestations that do not necessarily correspond to psychiatric illness. Anti‐N‐methyl‐D‐aspartate encephalitis is a good example, and atypical presentations of the disorder are particularly challenging. Abstract : Anti‐NMDAR encephalitis is a disorder characterized by psychiatric symptoms, cognitive impairment, movement disorders, and autonomic dysfunction; originally thought as a paraneoplastic syndrome. The classical clinical picture comprises five stages, but there are some milder or incomplete forms of the disorder. The current case is about an atypical presentation with ataxia and headache as predominant symptoms.