Association of labor induction or stimulation with infant mortality in women with failed versus successful trial of labor after prior cesarean*. (19th March 2013)

• Record Type: Journal Article
• Authors: Chen, Han-Yang; Chauhan, Suneet P.; Grobman, William A.; Ananth, Cande V.; Vintzileos, Anthony M.; Abuhamad, Alfred Z.
• Is Part Of: Journal of maternal-fetal & neonatal medicine. Volume 26:Number 12(2013:Dec.)
• Page Start: 1162
• Page End: 1165
• Publication Date: 2013-03-19
• Subjects: Infant mortality -- labor induction or augmentation -- trial of labor after cesarean; Obstetrics -- Periodicals; Perinatology -- Periodicals; Infants (Newborn) -- Diseases -- Periodicals; Neonatology -- Periodicals; 618.2
• DOI: 10.3109/14767058.2013.777700
• Languages: English
• ISSNs: 1476-7058

Abstract

Abstract: Objective : To compare infant mortality rates among women with a failed versus successful trial of labor after cesarean (TOLAC) following labor induction or stimulation. Study design : Using US linked birth and infant death cohort data (2000–2004), we identified women who delivered non-anomalous singleton births at 34–41 weeks with TOLAC whose labors were induced or stimulated. Multivariable log-binomial regression models were fitted to estimate the association between TOLAC success and infant mortality. Results : Of the 164, 113 women who underwent TOLAC, 41% were unsuccessful. After adjustment for potential confounding factors, a failed TOLAC was associated with a 1.4 fold (95% confidence interval [CI] 1.1, 1.7) increased risk of infant mortality. Conclusions : Among women undergoing labor induction or stimulation, a failed TOLAC is associated with higher likelihood of infant mortality.