Randomized Controlled Trial to Compare Two Bone Substitutes in the Treatment of Bony Dehiscences. (11th January 2012)

• Record Type: Journal Article
• Authors: Van Assche, Nele; Michels, Sofie; Naert, Ignace; Quirynen, Marc
• Is Part Of: Clinical implant dentistry and related research. Volume 15:Number 4(2013:Aug.)
• Page Start: 558
• Page End: 568
• Publication Date: 2012-01-11
• Subjects: bone augmentation -- guided bone regeneration -- maxilla -- SLActive -- two stage; Dental implants -- Periodicals; Dental Implantation -- Periodicals; Dental Implants -- Periodicals; 617.693
• DOI: 10.1111/j.1708-8208.2011.00408.x
• Languages: English
• ISSNs: 1523-0899

Abstract

ABSTRACT: Aim: This in vivo split‐mouth randomized controlled trial compared a synthetic bone substitute with a bovine bone mineral to cover bone dehiscences after implant insertion. Materials and Methods: Fourteen patients received four to six implants to support an overdenture. Two comparable dehiscences within the same patient were first covered with a layer of autogenous bone, followed by a layer of either Bio‐Oss® (group 1; Geistlich Pharma AG, Wolhusen, Switzerland) or Straumann BoneCeramic® (group 2; Institut Straumann AG, Basel, Switzerland) and sealed by a resorbable membrane. The change in vertical dimension of the defect was measured at implant placement and at abutment connection (6.5 months). Clinical and radiological parameters were evaluated up to 1 year of loading. Results: The vertical size of the defect at surgery was 6.4 ± 1.6 mm for group 1 and 6.4 ± 2.2 mm for group 2 sites, measured from the implant shoulder. After 6.5 months, the depth of the defect was reduced to 1.5 ± 1.2 mm and 1.9 ± 1.2 mm for group 1 and group 2 sites, respectively ( p > 0.05). No implants failed during follow‐up. Mean marginal bone loss over the SLActive surface was 0.94 mm (group 1), 0.81 mm (group 2), and 0.93 mm (group 3, no dehiscence) after 1 year of loading. Conclusion: Both bone substitutes behaved equally effectively.