68Ga-DOTANOC Focal Pulmonary Activity With No Corresponding CT Abnormality. (December 2016)

• Record Type: Journal Article
• Authors: Panagiotidis, Emmanouil; Seshadri, Nagabhushan; Fernando, Rashika; Healey, Priya; Vinjamuri, Sobhan
• Is Part Of: Clinical nuclear medicine. Volume 41:Number 12(2016)
• Publication Date: 2016-12
• Subjects: 68Ga-DOTANOC lung activity -- iatrogenic pulmonary microembolism -- medullary thyroid carcinoma -- negative contrast-enhanced CT; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000001416
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: A 28-year-old woman with medullary thyroid cancer treated with total thyroidectomy and bilateral central and right lateral neck nodal resection postoperatively had increasing calcitonin and carcinoembryonic antigen values. A 68 Ga-DOTANOC PET/CT study performed showed tracer-avid disease in the neck, mediastinal, and hilar lymph nodes. However, there were 3 tracer-avid foci in the lungs bilaterally, suggestive of lung metastases but with no corresponding abnormalities on low-dose CT. A negative contrast-enhanced CT of the lungs along with clinical and radiological follow-up confirmed that the lung activity was artifactual, demonstrating the possibility of 68 Ga-DOTANOC–avid iatrogenic pulmonary microembolism.