Successful outcome of three patients with sickle‐cell disease and fat embolism syndrome treated with intensive exchange transfusion. Issue 1 (20th December 2016)

• Record Type: Journal Article
• Authors: Greaves, Paul; Mathew, Vivek; Peters, Catherine; Rowe, Susan; Amos, Roger J.; Tsitsikas, Dimitris A.
• Is Part Of: Clinical case reports. Volume 5:Issue 1(2017)
• Page Start: 39
• Page End: 43
• Publication Date: 2016-12-20
• Subjects: Bone marrow necrosis -- fat embolism syndrome -- parvovirus B19 -- sickle cell -- transfusion; Medicine -- Periodicals; 616.09
• DOI: 10.1002/ccr3.727
• Languages: English
• ISSNs: 2050-0904

Abstract

Key Clinical Message: Fat embolism syndrome (FES) is a rare complication of sickle‐cell disease (SCD) associated with extremely high mortality rates. It affects predominantly non‐SS patients and those with previously mild disease. Rapid institution of exchange transfusion with an aim to reduce HbS to very low levels as soon as FES is suspected can be life‐saving. Abstract : Fat embolism syndrome (FES) is a rare complication of sickle‐cell disease (SCD) associated with extremely high mortality rates. It affects predominantly non‐SS patients and those with previously mild disease. Rapid institution of exchange transfusion with an aim to reduce HbS to very low levels as soon as FES is suspected can be life‐saving.