Cellulose Biorefinery Based on a Combined Catalytic and Biotechnological Approach for Production of 5‐HMF and Ethanol. Issue 3 (11th January 2017)

• Record Type: Journal Article
• Authors: Sorokina, Ksenia N.; Taran, Oxana P.; Medvedeva, Tatiana B.; Samoylova, Yuliya V.; Piligaev, Alexandr V.; Parmon, Valentin N.
• Is Part Of: ChemSusChem. Volume 10:Issue 3(2017)
• Page Start: 562
• Page End: 574
• Publication Date: 2017-01-11
• Subjects: 5-HMF -- biomass conversion -- biosynthesis -- ethanol -- heterogeneous catalysis; Green chemistry -- Periodicals; Sustainable engineering -- Periodicals; Chemistry -- Periodicals; Chemical engineering -- Periodicals; 660
• DOI: 10.1002/cssc.201601244
• Languages: English
• ISSNs: 1864-5631

Abstract

Abstract: In this study, a combination of catalytic and biotechnological processes was proposed for the first time for application in a cellulose biorefinery for the production of 5‐hydroxymethylfurfural (5‐HMF) and bioethanol. Hydrolytic dehydration of the mechanically activated microcrystalline cellulose over a carbon‐based mesoporous Sibunt‐4 catalyst resulted in moderate yields of glucose and 5‐HMF (21.1–25.1 and 6.6–9.4 %). 5‐HMF was extracted from the resulting mixture with isobutanol and subjected to ethanol fermentation. A number of yeast strains were isolated that also revealed high thermotolerance (up to 50 °C) and resistance to inhibitors found in the hydrolysates. The strains Kluyveromyces marxianus C1 and Ogataea polymorpha CBS4732 were capable of producing ethanol from processed catalytic hydrolysates of cellulose at 42 °C, with yields of 72.0±5.7 and 75.2±4.3 % from the maximum theoretical yield of ethanol, respectively. Abstract : Clean and effective : A cellulosic biorefinery process based on a catalytic and biotechnological approach is developed. Glucose (yield: 21.1–25.1 %) and 5‐hydroxymethylfurfural (5‐HMF, yield: 6.6–9.4 %) are produced over a carbon‐based catalyst. After 5‐HMF extraction, the latter is then fermented into ethanol by the thermotolerant yeast strains K. marxianus C1 and O. polymorpha CBS4732 at 42 °C, with yields of 72.0±5.7 and 75.2±4.3 %, respectively.