Box–Behnken designed adsorption based elution – unique separation process for commercially important acetyl shikonin from Arnebia nobilis. Issue 9 (22nd December 2014)

• Record Type: Journal Article
• Authors: Subramaniam, Shankar; Palanisamy, Anbumathi; Sivasubramanian, Aravind
• Is Part Of: RSC advances. Volume 5:Issue 9(2015)
• Page Start: 6265
• Page End: 6270
• Publication Date: 2014-12-22
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c4ra13570a
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : Box–Behnken optimized, adsorption based robust separation technique for acetyl shikonin (AS), a commercially important compound from industrial crop Arnebia nobilis . Abstract : Acetyl shikonin (AS), a pharmaceutically and commercially important compound, is a minor constituent in the industrial crop Arnebia nobilis . A Box–Behnken optimized, robust separation technique for AS was established by an adsorption based elution method. Optimized yields depict an increase of 78.9% total recovery of AS (97.8% pure), compared to conventional chromatography.