Β-Ketothioamides: efficient reagents in the synthesis of heterocycles. Issue 7 (23rd December 2014)

• Record Type: Journal Article
• Authors: Guo, Wei-Si; Wen, Li-Rong; Li, Ming
• Is Part Of: Organic & biomolecular chemistry. Volume 13:Issue 7(2015)
• Page Start: 1942
• Page End: 1953
• Publication Date: 2014-12-23
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c4ob02024c
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : β-Ketothioamides (KTAs) are versatile building blocks for the rapid construction of various heterocyclic compounds. Abstract : β-Ketothioamides (KTAs) are versatile building blocks for the rapid construction of various heterocyclic compounds. In the past decade, a number of successful reactions based on KTAs have been developed for the construction of heterocyclic skeletons under mild conditions. This minireview focuses on the annulation reactions of KTAs with dielectrophilic or dinucleophilic reagents. Multicomponent reactions using KTAs to construct various heterocycles are also the major contents in this review.