Synthesis and physico-chemical properties of the first water soluble Cu(ii)@hemicryptophane complex. Issue 7 (23rd December 2014)

• Record Type: Journal Article
• Authors: Schmitt, Aline; Collin, Solène; Bucher, Christophe; Maurel, Vincent; Dutasta, Jean-Pierre; Martinez, Alexandre
• Is Part Of: Organic & biomolecular chemistry. Volume 13:Issue 7(2015)
• Page Start: 2157
• Page End: 2161
• Publication Date: 2014-12-23
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c4ob02085e
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : A water-soluble metallo-enzyme model featuring a copper(ii ) site encaged in a closed-shell cavity of a hemicryptophane has been synthesized and studied. Abstract : A hemicryptophane ligand soluble in water at neutral pH was obtained thanks to the derivatization of the cyclotribenzylene unit with three carboxylate groups. The corresponding Cu(ii ) complex was then synthesized and its spectroscopic and electrochemical properties in water were investigated, showing that water solubilisation retains the geometry of the complex around the metal center but strongly affects its redox properties, compared to previously reported Cu(ii )@hemicryptophane complexes soluble in organic solvents.