NMR solution structure study of one saturated sulphur-containing amides from Glycosmis lucida. Issue 7 (3rd April 2017)

• Record Type: Journal Article
• Authors: Geng, Zhu-Feng; Yang, Kai; Li, Yin-Ping; Guo, Shan-Shan; You, Chun-Xue; Zhang, Wen-Juan; Zhang, Zhe; Du, Shu-Shan
• Is Part Of: Natural product research. Volume 31:Issue 7(2017)
• Page Start: 791
• Page End: 796
• Publication Date: 2017-04-03
• Subjects: NMR -- NOE -- sulphur-containing amides -- solution structure; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2016.1244196
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: One sulphur-containing amide (N-[2-(4-Hydroxyphenyl)-ethyl]-3-methanesulfonyl-N-methyl-propionamide) which was isolated from Glycosmis lucida Wall ex Huang had a different NMR profile with this kind of compounds' normal case. Based on the information obtained by nuclear magnetic resonance pectroscopy (NMR) and mass spectrometry (MS), its configurations in solution were investigated. The results indicated that the compound would have two stable configurations in solution as the double bond switched between C–N and C–O in an appropriate rate. This phenomenon was clearly exposed by the one dimension selective NOE (1D-NOE) experiments. This conclusion would play an active role in the structure analysis work of this kind of compounds. Abstract :