A plant solution to the CDK conundrum in the DNA damage response. (29th August 2016)
- Record Type:
- Journal Article
- Title:
- A plant solution to the CDK conundrum in the DNA damage response. (29th August 2016)
- Main Title:
- A plant solution to the CDK conundrum in the DNA damage response
- Authors:
- Desvoyes, Bénédicte
Gutierrez, Crisanto - Abstract:
- Abstract : To cope with DNA damage, proliferating cells have evolved sophisticated mechanisms including cell cycle arrest and activation of DNA repair. Paradoxically, various DNA damage response pathways are promoted by cyclin‐dependent kinase (CDK) activity, while cell cycle remains arrested. New work in The EMBO Journal shows that plant cells have evolved intricate ways to resolve this dilemma, by utilizing distinct and specialized CDKs for cell cycle progression and homologous recombination. Abstract : Halting the cell cycle yet allowing CDK stimulation of DNA repair creates a catch‐22 situation that can be solved by specialized cyclin‐CDK complexes.
- Is Part Of:
- EMBO journal. Volume 35:Number 19(2016)
- Journal:
- EMBO journal
- Issue:
- Volume 35:Number 19(2016)
- Issue Display:
- Volume 35, Issue 19 (2016)
- Year:
- 2016
- Volume:
- 35
- Issue:
- 19
- Issue Sort Value:
- 2016-0035-0019-0000
- Page Start:
- 2061
- Page End:
- 2063
- Publication Date:
- 2016-08-29
- Subjects:
- Molecular biology -- Periodicals
572.805 - Journal URLs:
- http://onlinelibrary.wiley.com/ ↗
- DOI:
- 10.15252/embj.201695348 ↗
- Languages:
- English
- ISSNs:
- 0261-4189
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3733.085000
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 1426.xml