Partner services in adults with acute and early HIV infection. (14th January 2017)

• Record Type: Journal Article
• Authors: Green, Nella; Hoenigl, Martin; Chaillon, Antoine; Anderson, Christy M.; Kosakovsky Pond, Sergei L.; Smith, Davey M.; Little, Susan J.
• Is Part Of: AIDS. Volume 31:Number 2(2017)
• Page Start: 287
• Page End: 293
• Publication Date: 2017-01-14
• Subjects: acute and early HIV infection -- contact tracing -- epidemiology -- HIV transmission -- men who have sex with men; AIDS (Disease) -- Periodicals; Acquired Immunodeficiency Syndrome; AIDS (Disease); Periodicals; Periodicals; 616.9792005
• DOI: 10.1097/QAD.0000000000001308
• Languages: English
• ISSNs: 0269-9370

Abstract

Abstract : Background: To examine the yield of HIV partner services provided to persons newly diagnosed with acute and early HIV infection (AEH) in San Diego, United States. Design: Observational cohort study. Methods: The study investigated the yield (i.e. number of new HIV and AEH diagnoses, genetically linked partnerships and high-risk uninfected partners) of partner services (confidential contact tracing) for individuals with AEH enrolled in the San Diego Primary Infection Resource Consortium 1996–2014. Results: A total of 107 of 574 persons with AEH (19%; i.e. index cases) provided sufficient information to recruit 119 sex partners. Fifty-seven percent of the 119 recruited partners were HIV infected, and 33% of the 119 were newly HIV diagnosed. Among those newly HIV diagnosed, 36% were diagnosed during AEH. There were no significant demographic or behavioral risk differences between HIV-infected and HIV-uninfected recruited partners. Genetic sequences were available for both index cases and partners in 62 partnerships, of which 61% were genetically linked. Partnerships in which both index case and partner enrolled within 30 days were more likely to yield a new HIV diagnosis ( P = 0.01) and to be genetically linked ( P < 0.01). Conclusion: Partner services for persons with AEH within 30 days of diagnosis represents an effective tool to find HIV-unaware persons, including those with AEH who are at greatest risk of HIV transmission.