Golden angle dual‐inversion recovery acquisition coupled with a flexible time‐resolved sparse reconstruction facilitates sequence timing in high‐resolution coronary vessel wall MRI at 3 T. Issue 3 (22nd February 2016)

• Record Type: Journal Article
• Authors: Ginami, Giulia; Yerly, Jérôme; Masci, Pier Giorgio; Stuber, Matthias
• Is Part Of: Magnetic resonance in medicine. Volume 77:Issue 3(2017)
• Page Start: 961
• Page End: 969
• Publication Date: 2016-02-22
• Subjects: Coronary vessel wall -- Compressed sensing -- Time‐resolved DIR; Nuclear magnetic resonance -- Periodicals; Electron paramagnetic resonance -- Periodicals; 616.07548
• DOI: 10.1002/mrm.26171
• Languages: English
• ISSNs: 0740-3194

Abstract

Abstract : Purpose: The need for performing dual‐inversion recovery (DIR) coronary vessel wall MRI in correspondence to minimal cardiac motion and optimal blood signal nulling is a major challenge. We propose to address this hurdle by combining DIR with a prolonged acquisition window in conjunction with a golden angle radial trajectory and k‐t sparse sensitivity encoding (SENSE) reconstruction to enable a flexible a‐posteriori selection of optimized imaging parameters. Methods: Coronary vessel wall data acquisition was performed with DIR golden angle radial imaging in n=15 healthy subjects. Images reconstructed using k‐t sparse SENSE and different reconstruction window settings were quantitatively (vessel wall conspicuity, thickness, acquisition, and reconstruction window settings) compared with those obtained with more conventional radial DIR imaging. Results: A flexible retrospective selection of the reconstruction window width and position improved vessel wall conspicuity with respect to baseline acquisitions ( P < 0.01). Vessel wall thickness remained unchanged ( P = nonsignificant (NS)). Temporal window widths were similar for both approaches ( P = NS), yet their position within the cardiac cycle differed significantly ( P < 0.02). Conclusions: A flexible DIR coronary vessel wall MRI technique that alleviates constraints associated with sophisticated sequence timing was proposed. When compared with a more conventional approach, the technique significantly improved image quality. Magn Reson Med 77:961–969, 2017. © 2016 International Society for Magnetic Resonance in Medicine