Self-assembled 4-(1, 2-diphenylbut-1-en-1-yl)aniline based nanoparticles: podophyllotoxin and aloin as building blocks. Issue 5 (17th January 2017)

• Record Type: Journal Article
• Authors: Fumagalli, Gaia; Christodoulou, Michael S.; Riva, Benedetta; Revuelta, Inigo; Marucci, Cristina; Collico, Veronica; Prosperi, Davide; Riva, Sergio; Perdicchia, Dario; Bassanini, Ivan; García-Argáez, Aida; Via, Lisa Dalla; Passarella, Daniele
• Is Part Of: Organic & biomolecular chemistry. Volume 15:Issue 5(2017)
• Page Start: 1106
• Page End: 1109
• Publication Date: 2017-01-17
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c6ob02591a
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : The ability of 4-(1, 2-diphenylbut-1-en-1-yl)aniline as a self-assembly inducer is reported. Abstract : The ability of 4-(1, 2-diphenylbut-1-en-1-yl)aniline as a self-assembly inducer is reported. The conjugation of this moiety with aloin or podophyllotoxin resulted in spherical nanoparticles that were characterized by Dynamic Light Scattering (DLS), Transmission Electron Microscopy (TEM) and NanoSight technology. A preliminary biological evaluation on two cancer cell lines is reported.