Detection of Fusarium-specific T cells in hematologic patients with invasive fusariosis. Issue 3 (March 2017)

• Record Type: Journal Article
• Authors: Vallerini, Daniela; Forghieri, Fabio; Lagreca, Ivana; Riva, Giovanni; Barozzi, Patrizia; Quadrelli, Chiara; Morselli, Monica; Bresciani, Paola; Cuoghi, Angela; Coluccio, Valeria; Maccaferri, Monica; Paolini, Ambra; Colaci, Elisabetta; Marasca, Roberto; Narni, Franco; Cellini, Monica; Beauvais, Anne; Latgè, Jean-Paul; Romani, Luigina; Iughetti, Lorenzo; Comoli, Patrizia; Campioli, Daniele; Trenti, Tommaso; Luppi, Mario; Potenza, Leonardo
• Is Part Of: Journal of infection. Volume 74:Issue 3(2017)
• Page Start: 314
• Page End: 318
• Publication Date: 2017-03
• Subjects: Infection -- Periodicals; Bacterial Infections -- Periodicals; Communicable Diseases -- Periodicals; Electronic journals; 616.905
• DOI: 10.1016/j.jinf.2016.12.008
• Languages: English
• ISSNs: 0163-4453

Abstract

Highlights: Invasive fusariosis (IF) is an emerging mould infection in hematologic patients. Fusarium -specific T cells are significantly higher in IF patients. In disseminated IF, specific T lymphocytes secretes pro-inflammatory cytokines. In pulmonary IF, we documented only the presence of IL10-secriting T cells. Fusarium -specific T cells could discriminate between different fungal pneumonias.