Asymmetric synthesis of 4-aryl-1, 2, 5-thiadiazolidin-3-one 1, 1-dioxides via Pd-catalyzed hydrogenation of cyclic ketimines. Issue 6 (19th January 2017)

• Record Type: Journal Article
• Authors: Zhu, Zhou-Hao; Chen, Meng-Lin; Jiang, Guo-Fang
• Is Part Of: Organic & biomolecular chemistry. Volume 15:Issue 6(2017)
• Page Start: 1325
• Page End: 1328
• Publication Date: 2017-01-19
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c6ob02655a
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : An efficient access to optically active sulfahydantoins, 4-aryl-1, 2, 5-thiadiazolidin-3-one 1, 1-dioxides, was developed through palladium-catalyzed asymmetric hydrogenation of the corresponding cyclic N -sulfonylketimines with up to 98% ee. Abstract : An efficient access to optically active sulfahydantoins, 4-aryl-1, 2, 5-thiadiazolidin-3-one 1, 1-dioxides, was developed through palladium-catalyzed asymmetric hydrogenation of the corresponding cyclic N -sulfonylketimines with up to 98% ee.