Synthesis and solution stability of water-soluble κ2N, κO-bis(3, 5-dimethylpyrazolyl)ethanol manganese(i) tricarbonyl bromide (CORM-ONN1). Issue 5 (19th January 2017)

• Record Type: Journal Article
• Authors: Mede, Ralf; Traber, Juliane; Klein, Moritz; Görls, Helmar; Gessner, Guido; Hoffmann, Patrick; Schmitt, Michael; Popp, Jürgen; Heinemann, Stefan H.; Neugebauer, Ute; Westerhausen, Matthias
• Is Part Of: Dalton transactions. Volume 46:Issue 5(2017)
• Page Start: 1684
• Page End: 1693
• Publication Date: 2017-01-19
• Subjects: Chemistry, Inorganic -- Periodicals; Chemistry, Physical and theoretical -- Periodicals; Chemistry, Inorganic -- Periodicals; 546.05
• DOI: 10.1039/c6dt03551e
• Languages: English
• ISSNs: 1477-9226

Abstract

Abstract : The 2, 2-bis(3, 5-dimethyl-1-pyrazolyl)ethanol heteroscorpionate ligand stabilizes a water-soluble and quite non-toxic photoCORM. Abstract : The reaction of (OC)5 MnBr with bis(3, 5-dimethyl-1-pyrazolyl)methane yields [{(Pz Me2 )2 CH2 }Mn(CO)3 Br] (1 ). The use of tridentate heteroscorpionates such as bis(3, 5-dimethyl-1-pyrazolyl)acetic acid and 2, 2-bis(3, 5-dimethyl-1-pyrazolyl)ethanol leads to the formation of mononuclear [(OC)3 Mn{(Pz Me2 )2 CH–CO2 }] (2 ) and [(OC)3 Mn{(Pz Me2 )2 CH–CH2 OH}]Br (3, CORM-ONN1). Salt-like photoCORM3 is soluble in aqueous media up to a concentration of 200 μM, non-toxic up to an approx. 65 μM solution and releases all carbonyl ligands upon irradiation. The molecular complexes1 and2 are insoluble in aqueous solutions. CORM-ONN1 (3 ) slowly degrades in methanol yielding iCORM4, consisting of the complex cation [{(Pz Me2 )2 CH–CH2 OH}{(Pz Me2 )2 CH–CH2 O}Mn] + and the [Mn(CO)5 ] − counter anion with the cations linked to a dimeric unit by intermolecular hydrogen bridges between the alcohol and alkoxide functionalities.