All-in-one thermometer-heater up-converting platform YF3:Yb3+, Tm3+ operating in the first biological window. Issue 6 (26th January 2017)

• Record Type: Journal Article
• Authors: Suo, Hao; Hu, Fangfang; Zhao, Xiaoqi; Zhang, Zhiyu; Li, Ting; Duan, Changkui; Yin, Min; Guo, Chongfeng
• Is Part Of: Journal of materials chemistry. Volume 5:Issue 6(2017)
• Page Start: 1501
• Page End: 1507
• Publication Date: 2017-01-26
• Subjects: Materials -- Periodicals; Chemistry, Analytic -- Periodicals; Optical materials -- Research -- Periodicals; Electronics -- Materials -- Research -- Periodicals; 543.0284
• DOI: 10.1039/c6tc05449h
• Languages: English
• ISSNs: 2050-7526

Abstract

Abstract : The combination of real-time diagnosis and therapy in an YF3 :Tm 3+ /Yb 3 up-converting platform with improved thermometry and photo-thermal ability is achieved through optimizing doping dosages. Abstract : Achieving the combination of real-time diagnosis and therapy in one up-converting platform with sensitive thermometry and efficient heat production is a critical step towards photo-thermal therapy (PTT). Here, the potentiality of truncated octahedral YF3 :Tm 3+ /Yb 3+ micro-crystals as thermometers operating in the first biological window (BW-I) was evaluated on the basis of a thermo-responsive fluorescence intensity ratio (FIR) of far-red to NIR emission from completely separated 3 F2, 3 / 3 H4 → 3 H6 transitions. The probabilities of cross-relaxation (CR) processes related to 3 F2, 3 / 3 H4 levels were greatly enhanced by increasing the Yb 3+ content, leading to an increase of more than three times in the absolute sensitivity within the physiological temperature range. Photo-thermal effects were also assessed by monitoring the variation of temperature around the samples as functions of the Yb 3+ dosage, excitation time and density of 980 nm laser diodes. These results offer a promising strategy to optimize the thermal sensitivity and optical heating ability, which indicates that the present UC platform has great potential applications in PTT as real-time thermometers and photo-thermal agents.