A red-NIR fluorescent dye detecting nuclear DNA G-quadruplexes: in vitro analysis and cell imaging. Issue 14 (2nd February 2017)
- Record Type:
- Journal Article
- Title:
- A red-NIR fluorescent dye detecting nuclear DNA G-quadruplexes: in vitro analysis and cell imaging. Issue 14 (2nd February 2017)
- Main Title:
- A red-NIR fluorescent dye detecting nuclear DNA G-quadruplexes: in vitro analysis and cell imaging
- Authors:
- Doria, F.
Nadai, M.
Zuffo, M.
Perrone, R.
Freccero, M.
Richter, S. N. - Abstract:
- Abstract : Light-up of nuclear G-quadruplex DNA in cells by an aggregating and red/NIR emitting dye. Abstract : Aggregation, red-NIR emission and light-up upon nucleic acid G-quadruplex binding have been investigated for a prototype core-extended naphthalene diimide, which is capable of fast cellular entry and nucleolar localization. Both high-level colocalization with an anti-G-quadruplex antibody and nucleolin displacement reveal that the compound targets and thus makes visible nuclear DNA G-quadruplexes.
- Is Part Of:
- Chemical communications. Volume 53:Issue 14(2017)
- Journal:
- Chemical communications
- Issue:
- Volume 53:Issue 14(2017)
- Issue Display:
- Volume 53, Issue 14 (2016)
- Year:
- 2016
- Volume:
- 53
- Issue:
- 14
- Issue Sort Value:
- 2016-0053-0014-0000
- Page Start:
- 2268
- Page End:
- 2271
- Publication Date:
- 2017-02-02
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c6cc08492c ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 1514.xml