Emergence of Copper‐Mediated Formation of C–C Bonds. Issue 2 (21st July 2016)

• Record Type: Journal Article
• Authors: Maaliki, Carine; Thiery, Emilie; Thibonnet, Jérôme
• Is Part Of: European journal of organic chemistry. Issue 2(2017)
• Page Start: 209
• Page End: 228
• Publication Date: 2016-07-21
• Subjects: Synthetic methods -- C–C coupling -- Dehydrogenative coupling -- Decarboxylative coupling -- Domino reactions -- Copper; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.201600540
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract : Copper‐catalyzed cross‐coupling reactions have found widespread application in carbon–carbon or carbon–heteroatom bond formation. The relatively low toxicity, ease of handling, and low cost of these versatile complexes make them attractive for the elaboration of new methodologies and for the obtaining of new compounds. We focus on recent methods for the copper‐mediated formation of carbon–carbon bonds illustrated by different coupling reactions: cross‐dehydrogenative coupling, decarboxylative cross‐coupling, Sonogashira‐type reactions, Suzuki‐type reactions, and Neigishi‐type reactions. Domino reactions and, finally, more atypical reactions are also illustrated. Abstract : An overview of copper‐catalyzed C–C bond reactions through the main recently developed methodologies is presented.