A rapid access to substituted oxazoles via PIFA-mediated oxidative cyclization of enamides. Issue 9 (2nd March 2017)
- Record Type:
- Journal Article
- Title:
- A rapid access to substituted oxazoles via PIFA-mediated oxidative cyclization of enamides. Issue 9 (2nd March 2017)
- Main Title:
- A rapid access to substituted oxazoles via PIFA-mediated oxidative cyclization of enamides
- Authors:
- Kamiya, Midori
Sonoda, Motohiro
Tanimori, Shinji - Abstract:
- Abstract: A facile and rapid access to multi-substituted oxazoles has been achieved under mild reaction conditions in a short reaction time. Reaction of enamides1 with [bis(trifluoroacetoxy)iodo]benzene (PIFA) in trifluoroethanol (TFE) at room temperature for 15 min afforded the desired oxazoles2 in moderate to excellent yields (58–98%). A wide range of functional group tolerance has been observed for these transformations. Graphical abstract:
- Is Part Of:
- Tetrahedron. Volume 73:Issue 9(2017)
- Journal:
- Tetrahedron
- Issue:
- Volume 73:Issue 9(2017)
- Issue Display:
- Volume 73, Issue 9 (2017)
- Year:
- 2017
- Volume:
- 73
- Issue:
- 9
- Issue Sort Value:
- 2017-0073-0009-0000
- Page Start:
- 1247
- Page End:
- 1254
- Publication Date:
- 2017-03-02
- Subjects:
- Oxazole -- Hypervalent iodine -- Enamide -- Oxidative cyclization -- PIFA
Chemistry, Organic -- Periodicals
547.005 - Journal URLs:
- http://www.elsevier.com/journals ↗
- DOI:
- 10.1016/j.tet.2017.01.027 ↗
- Languages:
- English
- ISSNs:
- 0040-4020
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 8796.850000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 714.xml