Regioselective hydrothiolation of terminal acetylene catalyzed by magnetite (Fe3O4) nanoparticles. Issue 4 (16th February 2017)

• Record Type: Journal Article
• Authors: Rocha, Manuela S. T.; Rafique, Jamal; Saba, Sumbal; Azeredo, Juliano B.; Back, Davi; Godoi, Marcelo; Braga, Antonio L.
• Is Part Of: Synthetic communications. Volume 47:Issue 4(2017)
• Page Start: 291
• Page End: 298
• Publication Date: 2017-02-16
• Subjects: Acetylenes -- catalysis -- magnetite (Fe3O4) -- nanoparticles -- thioethers; Organic compounds -- Synthesis -- Periodicals; Chemistry, Organic; Synthesis; 547.205
• DOI: 10.1080/00397911.2016.1262421
• Languages: English
• ISSNs: 0039-7911

Abstract

ABSTRACT: Herein, we report a new and solvent-free methodology for the preparation of vinyl thioethers from terminal alkynes and thiols, using magnetite (Fe3 O4 ) nanoparticles as a recyclable catalyst. With this greener method, the desired vinyl thioethers were achieved in good yields and with good stereoselectivity. In addition, the catalyst was easily recovered using a simple external magnet and reused for further catalytic reactions without significant loss of activity up to the fifth cycle. GRAPHICAL ABSTRACT: