Palladium-catalyzed three-component tandem cyclization of buta-2, 3-dien-1-ol, aryl iodides, and imines: an efficient protocol for the synthesis of oxazolidine derivatives. Issue 12 (23rd January 2017)

• Record Type: Journal Article
• Authors: Hou, Yunlei; Qin, Mingze; Yang, Xiuxiu; Shen, Qi; Zhao, Yanfang; Liu, Yajing; Gong, Ping
• Is Part Of: RSC advances. Volume 7:Issue 12(2017)
• Page Start: 7401
• Page End: 7405
• Publication Date: 2017-01-23
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c6ra27993g
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : An efficient three-component tandem cyclization reaction for the synthesis of highly substituted oxazolidines was achieved through the Pd 0 -catalyzed cyclization of buta-2, 3-dien-1-ol with aryl iodides and imines. Abstract : An efficient three-component tandem cyclization reaction for the synthesis of highly substituted oxazolidines was achieved through the Pd 0 -catalyzed cyclization of buta-2, 3-dien-1-ol with aryl iodides and imines. A range of R 1 and R 2 functional groups is well-tolerated while affording cyclization products in moderate yields and with moderate to high diastereoselectivities.