'Aggregation induced emission' active iridium(iii) complexes with applications in mitochondrial staining. Issue 10 (17th January 2017)

• Record Type: Journal Article
• Authors: Alam, Parvej; Dash, Subhra; Climent, Claudia; Kaur, Gurpreet; Choudhury, Angshuman Roy; Casanova, David; Alemany, Pere; Chowdhury, Rajdeep; Laskar, Inamur Rahaman
• Is Part Of: RSC advances. Volume 7:Issue 10(2017)
• Page Start: 5642
• Page End: 5648
• Publication Date: 2017-01-17
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c6ra24792j
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : Synthesized two new bis-cyclometalated iridium(iii ) complexes exhibiting strong AIE, studied their luminescence by spectroscopy and quantum chemical calculations and applied as a non-toxic bio-imaging probe for mitochondrial staining. Abstract : Two new bis-cyclometalated iridium(iii ) complexes, [Ir(F2 ppy)2 (L)] and [Ir(ppy)2 (L)], where F2 ppy = 2-(2′, 4′-difluoro)phenylpyridine, ppy = 2-phenylpyridine and L = 1, 2-((pyridin-2-ylimino)methyl)phenol, have been designed and synthesized by a convenient route. We have univocally characterized their structure by 1 H NMR, 19 F NMR, HRMS and SXRD. Both complexes exhibit strong 'Aggregation Induced Emission (AIE)' activity, which has been investigated using spectroscopy measurements, ab initio quantum chemical calculations and by analysing their crystal packing. One of the complexes has been shown to have a potential application as a non-toxic bio-imaging probe for mitochondrial staining.