MALDI-imaging enables direct observation of kinetic and thermodynamic products of mixed peptide fiber assembly. Issue 10 (19th January 2017)

• Record Type: Journal Article
• Authors: Medini, Karima; West, Brandi; Williams, David E.; Brimble, Margaret A.; Gerrard, Juliet A.
• Is Part Of: Chemical communications. Volume 53:Issue 10(2017)
• Page Start: 1715
• Page End: 1718
• Publication Date: 2017-01-19
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c6cc10146a
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : The first use of MALDI-imaging, as a snapshot tool to characterize multicomponent self-assembling peptide fibers. Abstract : Controlling the self-assembly of multicomponent systems provides a key to designing new materials and understanding the molecular complexity of biology. Here, we demonstrate the first use of MALDI-imaging to characterize a multicomponent self-assembling peptide fiber. Observations of mixed peptide systems over time demonstrate how simple sequence variation can change the balance between kinetic and thermodynamic products.