Adamantyl aziridines via aza-Michael initiated ring closure (aza-MIRC) reaction. Issue 8 (23rd February 2017)
- Record Type:
- Journal Article
- Title:
- Adamantyl aziridines via aza-Michael initiated ring closure (aza-MIRC) reaction. Issue 8 (23rd February 2017)
- Main Title:
- Adamantyl aziridines via aza-Michael initiated ring closure (aza-MIRC) reaction
- Authors:
- Fedotova, Alena I.
Komarova, Tatiana A.
Romanov, Alexey R.
Ushakov, Igor A.
Legros, Julien
Maddaluno, Jacques
Rulev, Alexander Yu. - Abstract:
- Abstract: An efficient one-pot synthesis of functionalized adamantylaziridines by aza-Michael initiated ring closure (aza-MIRC) reaction of 1-aminoadamantane with α- halogenated Michael acceptors is described. The reaction goes through an aza-Michael intermediate that undergoes an intramolecular nucleophilic substitution. Expectedly, high pressure exerts a beneficial influence in the case of sterically hindered reagents. Graphical abstract:
- Is Part Of:
- Tetrahedron. Volume 73:Issue 8(2017)
- Journal:
- Tetrahedron
- Issue:
- Volume 73:Issue 8(2017)
- Issue Display:
- Volume 73, Issue 8 (2017)
- Year:
- 2017
- Volume:
- 73
- Issue:
- 8
- Issue Sort Value:
- 2017-0073-0008-0000
- Page Start:
- 1120
- Page End:
- 1126
- Publication Date:
- 2017-02-23
- Subjects:
- Aza-Michael addition -- Aziridines -- Aminoadamantane
Chemistry, Organic -- Periodicals
547.005 - Journal URLs:
- http://www.elsevier.com/journals ↗
- DOI:
- 10.1016/j.tet.2017.01.006 ↗
- Languages:
- English
- ISSNs:
- 0040-4020
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 8796.850000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 2687.xml