Cancer of mice and men: old twists and new tails. Issue 1 (10th April 2013)

• Record Type: Journal Article
• Authors: van der Weyden, Louise; Adams, David J
• Is Part Of: Journal of pathology. Volume 230:Issue 1(2013)
• Page Start: 4
• Page End: 16
• Publication Date: 2013-04-10
• Subjects: mouse cancer model -- transgenic -- knockout -- insertional mutagenesis; Pathology -- Periodicals; 616.07
• DOI: 10.1002/path.4184
• Languages: English
• ISSNs: 0022-3417

Abstract

Abstract: In this review we set out to celebrate the contribution that mouse models of human cancer have made to our understanding of the fundamental mechanisms driving tumourigenesis. We take the opportunity to look forward to how the mouse will be used to model cancer and the tools and technologies that will be applied, and indulge in looking back at the key advances the mouse has made possible. Copyright © 2013 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.