Successful renal retransplantation after graft loss from BK polyomavirus infection in a human immunodeficiency virus‐positive patient. Issue 6 (10th November 2016)

• Record Type: Journal Article
• Authors: Barthélemy, Aurore; Bouvier, Nicolas; Verdon, Renaud; Chatelet, Valérie; Hurault de Ligny, Bruno
• Is Part Of: Transplant infectious disease. Volume 18:Issue 6(2016)
• Page Start: 946
• Page End: 949
• Publication Date: 2016-11-10
• Subjects: BK polyomavirus -- BKV nephropathy -- HIV -- immunosuppression -- kidney transplantation; Transplantation of organs, tissues, etc -- Complications -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; 617.01
• DOI: 10.1111/tid.12615
• Languages: English
• ISSNs: 1398-2273

Abstract

Abstract: We report the case of a human immunodeficiency virus‐seropositive patient whose initial kidney transplant failed because of BK polyomavirus‐induced nephropathy, and who underwent a second transplantation 3 years later. BK viruria was detected 1 day after transplantation. After 1 month, BK viremia developed along with a donor‐specific antibody. After decreasing tacrolimus and mycophenolic acid and 2 courses of intravenous immunoglobulins, BK viremia and donor‐specific antibody permanently disappeared, with stable renal function.