ChemInform Abstract: Concise Synthesis of Carbazole‐1, 4‐quinones and Evaluation of Their Antiproliferative Activity Against HCT‐116 and HL‐60 Cells. Issue 51 (5th December 2016)

• Record Type: Journal Article
• Authors: Nishiyama, Takashi; Hatae, Noriyuki; Yoshimura, Teruki; Takaki, Sawa; Abe, Takumi; Ishikura, Minoru; Hibino, Satoshi; Choshi, Tominari
• Is Part Of: ChemInform. Volume 47:Issue 51(2016)
• Page Start: no
• Page End: no
• Publication Date: 2016-12-05
• Subjects: fused pyrrole derivatives -- ring closure reactions, annulation reactions -- metathesis reactions -- cascade reactions, domino reactions, tandem reactions -- oxidation, dehydrogenation -- anticarcinogenic activity, anticancer activity; Chemistry -- Abstracts -- Periodicals; 540.5
• DOI: 10.1002/chin.201651136
• Languages: English
• ISSNs: 0931-7597

Abstract

Abstract: Carbazole‐1, 4‐quinone alkaloids, koeniginequinone A (IIa) and B (IIb), are obtained by a three‐step total synthesis containing tandem ring‐closing metathesis with dehydrogenation reaction as key step.