Pathological and physiological muscle co-activation during active elbow extension in children with unilateral cerebral palsy. Issue 1 (January 2017)

• Record Type: Journal Article
• Authors: Sarcher, A.; Raison, M.; Leboeuf, F.; Perrouin-Verbe, B.; Brochard, S.; Gross, R.
• Is Part Of: Clinical neurophysiology. Volume 128:Issue 1(2017:Jan.)
• Page Start: 4
• Page End: 13
• Publication Date: 2017-01
• Subjects: AROM active range of motion -- CA co-activation -- CP cerebral palsy -- EAccP extension acceleration phase -- EDecP extension deceleration phase -- EF extension/flexion -- EMG electromyography -- IUL involved upper limb -- MACS Manual Ability Classification System -- MAS Modified Ashworth Scale -- PPV Percentage to Peak Velocity -- SUCP Spastic Unilateral Cerebral Palsy -- TD Typically Developing; Unilateral spastic cerebral palsy -- Muscle co-activation -- Surface electromyography -- Elbow extension -- Antagonist muscle; Neurophysiology -- Periodicals; Electroencephalography -- Periodicals; Electromyography -- Periodicals; Neurology -- Periodicals; 612.8
• DOI: 10.1016/j.clinph.2016.10.086
• Languages: English
• ISSNs: 1388-2457

Abstract

Highlights: Muscle co-activation in children with cerebral palsy was pathological and physiological. Pathological co-activation increased with elbow extension speed. Pathological co-activation was more pronounced in brachioradialis than biceps brachii. Abstract: Objective: To address the roles and mechanisms of co-activation in two flexor/extensor pairs during elbow extension in children with cerebral palsy (CP). Methods: 13 Typically Developing (TD) and 13 children with unilateral spastic CP performed elbow extension/flexion at different speeds. Elbow angle and velocity were recorded using a 3D motion analysis system. The acceleration and deceleration phases of extension were analyzed. Co-activation of the brachioradialis/triceps and biceps/triceps pairs was computed for each phase from surface electromyographic signals. Statistical analysis involved linear mixed effects models and Spearman rank correlations. Results: During the acceleration phase, there was strong co-activation in both muscle pairs in the children with CP, which increased with speed. Co-activation was weak in the TD children and it was not speed-dependent. During the deceleration phase, co-activation was strong and increased with speed in both groups; co-activation of brachioradialis/triceps was stronger in children with CP, and was negatively correlated with extension range and positively correlated with flexor spasticity. Conclusions: Abnormal patterns of co-activation in children with CP were found throughout the entire movement. Co-activation was specific to the movement phase and to each flexor muscle. Significance: Co-activation in children with CP is both physiological and pathological.