Do X‐linked diseases affect periodontal health?. (13th December 2012)

• Record Type: Journal Article
• Authors: Chien, Hua‐Hong; Hart, Thomas C.
• Is Part Of: Periodontology 2000. Volume 61(2013)
• Page Start: 266
• Page End: 278
• Publication Date: 2012-12-13
• Subjects: Periodontics -- Periodicals; 617.632
• DOI: 10.1111/j.1600-0757.2012.00441.x
• Languages: English
• ISSNs: 0906-6713

Abstract

Abstract: Genetic factors play an important etiologic role in destructive periodontal diseases. There have been reports that sex chromosomes, especially disorders associated with the X chromosome, affect periodontal health. Although numerous X‐linked diseases have been reported to be associated with various periodontal diseases, the association of gingivitis and/or periodontitis with these genetic syndromes should be considered tenuous and raises the question of whether the periodontal manifestation truly arises from an underlying X‐linked genetic etiology. A brief overview of genetics in relation to sex chromosomes and putative X‐linked genetic periodontal diseases is given.