Trimetaphosphate and imidazole—Possible reagents in prebiotic peptide synthesis. (1st December 2016)

• Record Type: Journal Article
• Authors: Serov, Nikita Yu.; Shtyrlin, Valery G.; Khayarov, Khasan R.
• Is Part Of: Phosphorus, sulfur, and silicon and the related elements. Volume 191:Number 11/12(2016)
• Page Start: 1558
• Page End: 1559
• Publication Date: 2016-12-01
• Subjects: Peptide synthesis -- trimetaphosphate -- imidazole; Sulfur compounds -- Periodicals; Organosulfur compounds -- Periodicals; Phosphorus compounds -- Periodicals; Organophosphorus compounds -- Periodicals; Silicon compounds -- Periodicals; Organosilicon compounds -- Periodicals; 546
• DOI: 10.1080/10426507.2016.1213258
• Languages: English
• ISSNs: 1042-6507

Abstract

GRAPHICAL ABSTRACT: Abstract: To develop the prebiotic peptide synthesis problem the oligopeptides formation kinetics in the glycine – sodium trimetaphosphate – imidazole system in water has been investigated in flow and batch conditions at different temperatures and pH values. The presence of sodium trimetaphosphate and alkaline conditions are necessary for oligoglycines formation. Imidazole increases yields of oligopeptides. The system investigated may be used as a good model for peptide synthesis in prebiotic conditions.