In Vitro Gene Delivery with Large Porous Silicon Nanoparticles Fabricated Using Cost‐Effective, Metal‐Assisted Chemical Etching. Issue 3 (7th November 2016)

• Record Type: Journal Article
• Authors: Wareing, Nancy; Szymanski, Kyle; Akkaraju, Giridhar R.; Loni, Armando; Canham, Leigh T.; Gonzalez‐Rodriguez, Roberto; Coffer, Jeffery L.
• Is Part Of: Small. Volume 13:Issue 3(2017)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2016-11-07
• Subjects: gene delivery -- nanomedicine -- porous silicon -- stain etching -- surface modification; Nanotechnology -- Periodicals; Nanoparticles -- Periodicals; Microtechnology -- Periodicals; 620.5
• DOI: 10.1002/smll.201602739
• Languages: English
• ISSNs: 1613-6810

Abstract

Abstract : The cytocompatibility, cell membrane affinity, and plasmid DNA delivery from surface oxidized, metal‐assisted stain‐etched mesoporous silicon nanoscale particles (pSiNPs) to human embryonic kidney (HEK293) cells is demonstrated, suggesting the possibility of using such material for targeted transfection and drug delivery.