Audio‐visual multisensory training enhances visual processing of motion stimuli in healthy participants: an electrophysiological study. (31st March 2016)

• Record Type: Journal Article
• Authors: Grasso, Paolo A.; Benassi, Mariagrazia; Làdavas, Elisabetta; Bertini, Caterina
• Editors: Foxe, John
• Is Part Of: European journal of neuroscience. Volume 44:Number 10(2016:Nov.)
• Page Start: 2748
• Page End: 2758
• Publication Date: 2016-03-31
• Subjects: audio‐visual integration -- dorsal‐extrastriate pathway -- motion discrimination -- N1 -- superior colliculus; Nervous system -- Periodicals; 612.8
• DOI: 10.1111/ejn.13221
• Languages: English
• ISSNs: 0953-816X

Abstract

Abstract: Evidence from electrophysiological and imaging studies suggests that audio‐visual (AV) stimuli presented in spatial coincidence enhance activity in the subcortical colliculo‐dorsal extrastriate pathway. To test whether repetitive AV stimulation might specifically activate this neural circuit underlying multisensory integrative processes, electroencephalographic data were recorded before and after 2 h of AV training, during the execution of two lateralized visual tasks: a motion discrimination task, relying on activity in the colliculo‐dorsal MT pathway, and an orientation discrimination task, relying on activity in the striate and early ventral extrastriate cortices. During training, participants were asked to detect and perform a saccade towards AV stimuli that were disproportionally allocated to one hemifield (the trained hemifield). Half of the participants underwent a training in which AV stimuli were presented in spatial coincidence, while the remaining half underwent a training in which AV stimuli were presented in spatial disparity (32°). Participants who received AV training with stimuli in spatial coincidence had a post‐training enhancement of the anterior N1 component in the motion discrimination task, but only in response to stimuli presented in the trained hemifield. However, no effect was found in the orientation discrimination task. In contrast, participants who received AV training with stimuli in spatial disparity showed no effects on either task. The observed N1 enhancement might reflect enhanced discrimination for motion stimuli, probably due to increased activity in the colliculo‐dorsal MT pathway induced by multisensory training. Abstract : A training with spatially coincident audio‐visual (AV) stimuli increases the N1 component in response to motion stimuli in the trained hemifield, in a task relying on the activity in the colliculo‐dorsal MT pathway (Motion discrimination task). No enhancement is found in a task relying on the activity of the striate and early ventral extrastriate cortices (Orientation discrimination task). No post‐training effect is found after a training with spatially disparate AV stimuli in both tasks.