Malignant pleural mesothelioma with lacrimal gland metastasis. (16th July 2016)

• Record Type: Journal Article
• Authors: Hanafi, Hanida; Verdijk, Rob M.; Paridaens, Dion
• Is Part Of: Acta ophthalmologica. Volume 94:Number 8(2016)
• Page Start: 836
• Page End: 838
• Publication Date: 2016-07-16
• Subjects: chemo and radiotherapy -- lacrimal gland -- malignant mesothelioma -- metastasis; Ophthalmology -- Periodicals; 617.7005
• DOI: 10.1111/aos.13163
• Languages: English
• ISSNs: 1755-375X

Abstract

Abstract: Purpose: To describe a rare clinical case of biopsy‐proven metastatic mesothelioma of the lacrimal gland which responded well to chemo and radiation therapy. Methods: Interventional case report. Results: A 55‐year‐old woman with an untreated malignant biopsy‐proven pleural mesothelioma presented with right proptosis, diplopia and hypoglobus. Magnetic resonance imaging showed an aggressive lacrimal gland tumour with bony erosion. A biopsy concluded a diagnosis of metastatic mesothelioma of the lacrimal gland. Her lacrimal and lung tumours showed a marked regression following palliative chemo (carboplatin) and radiation therapy. Conclusions: Malignant pleural mesothelioma may metastasize to the orbit, including the lacrimal gland. A combined chemo and radiation therapy may reduce the size of the metastatic and primary tumour.