Using a Redox Modality to Connect Synthetic Biology to Electronics: Hydrogel‐Based Chemo‐Electro Signal Transduction for Molecular Communication. Issue 1 (18th November 2016)

• Record Type: Journal Article
• Authors: Liu, Yi; Tsao, Chen‐Yu; Kim, Eunkyoung; Tschirhart, Tanya; Terrell, Jessica L.; Bentley, William E.; Payne, Gregory F.
• Is Part Of: Advanced healthcare materials. Volume 6:Issue 1(2017)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2016-11-18
• Subjects: electrodeposition -- hydrogels -- molecular communication -- redox -- synthetic biology; Biomedical materials -- Periodicals; 610.28
• DOI: 10.1002/adhm.201600908
• Languages: English
• ISSNs: 2192-2640

Abstract

Abstract : A hydrogel‐based dual film coating is electrofabricated for transducing bio‐relevant chemical information into electronical output. The outer film has a synthetic biology construct that recognizes an external molecular signal and transduces this input into the expression of an enzyme that converts redox‐inactive substrate into a redox‐active intermediate, which is detected through an amplification mechanism of the inner redox‐capacitor film.