An Iron(II) Chloride‐Promoted Radical Cascade Methylation or α‐Chloro‐β‐methylation of N‐Arylacrylamides with Dimethyl Sulfoxide. Issue 2 (4th January 2017)

• Record Type: Journal Article
• Authors: Li, Zejiang; Cui, Xiaosong; Niu, Lin; Ren, Yingming; Bian, Menghua; Yang, Xuebiao; Yang, Biao; Yan, Qinqin; Zhao, Jincan
• Is Part Of: Advanced synthesis & catalysis. Volume 359:Issue 2(2017)
• Page Start: 246
• Page End: 249
• Publication Date: 2017-01-04
• Subjects: N-arylacrylamides -- α-chloro-β-methylation -- cyclization -- methylation -- radical reactions; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201601001
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: A free radical‐initiated methylation and/or α‐chloro‐β‐methylation of N ‐arylacrylamides with dimethyl sulfoxide under the analogous Fenton reaction condition has been developed, which provides an effective and facile cascade strategy for the synthesis of oxindoles and chlorinated amides. Abstract :